SYLX52

http://proteus.dcc.ufmg.br/result/id/SYLX52

272

pairs of mutations were found

Filters:

Mutation Template Chain R1 R2 RMSD ΔΔG Clash Show template
A129S/L133D 4iqg B S37 D41 0.46 4.225 No
A129S/L133H 4toh B S126 H130 0.33 3.845 No
A129S/L133K 4kn8 B S26 K30 0.21 3.81 No
A129T/L133H 3vpc C T148 H152 0.25 3.659 No
A129Y/L133T 4cae C Y88 T92 0.22 3.623 No
A146D/I150N 4nac B D65 N69 0.41 3.897 No
A146S/I150H 4toh B S126 H130 0.27 4.029 No
A146S/I150K 4kn8 B S26 K30 0.16 4.019 No
A146S/I150Y 3r3r A S159 Y163 0.42 3.556 No
D127R/V131R 1qtx B R12 R16 0.24 -1.287 No
D127R/V131N 3ix8 A R137 N141 0.48 -1.234 No
D127N/V131T 3bol B N190 T194 0.39 0.298 No
D127Q/V131R 2x1c B Q196 R200 0.31 -1.506 No
D127Q/V131Y 1c27 A Q130 Y134 0.28 -0.431 No
D127E/V131Y 3ub9 A E48 Y52 0.16 -0.358 No
D127H/V131S 1p7g H H87 S91 0.46 -0.605 No
D127H/V131N 4hmm B H177 N181 0.24 -1.023 No
D127H/V131Y 1xh8 A H142 Y146 0.19 -0.41 No
D127H/V131W 4enq D H251 W255 0.2 -0.308 No
D127K/V131H 2ifq A K39 H43 0.34 -0.578 No
D127S/V131H 4toh B S126 H130 0.27 0.37 No
D127S/V131K 4kn8 B S26 K30 0.27 -1.165 No
D127T/V131H 3vpc C T148 H152 0.2 0.0 No
D127T/V131R 3mux A T233 R237 0.5 -1.461 No
D127W/V131S 2eij C W146 S150 0.25 -0.947 No
D127W/V131W 4tf4 A W287 W291 0.34 -0.785 No
D127W/V131Q 2q79 A W339 Q343 0.27 -1.215 No
D127W/V131T 1c5v A W237 T241 0.39 -0.665 No
D127Y/V131T 4cae C Y88 T92 0.32 -0.564 No
D127Y/V131Y 3i0z A Y292 Y296 0.45 -0.72 No
N116H/E128H 5i14 A H73 H85 0.36 1.528 No
I100N/F104T 3bol B N190 T194 0.37 3.062 No
I100H/F104S 1p7g H H87 S91 0.39 3.427 No
I100H/F104N 4hmm B H177 N181 0.24 2.874 No
I100S/F104D 4iqg B S37 D41 0.48 3.225 No
I100S/F104H 4toh B S126 H130 0.18 3.46 No
I100S/F104K 4kn8 B S26 K30 0.18 3.114 No
I100Y/F104T 4cae C Y88 T92 0.21 2.88 No
M106R/V111T 1vmg A R23 T28 0.39 2.572 No
N116R/M120N 3ix8 A R137 N141 0.45 1.736 No
N116Q/M120R 2x1c B Q196 R200 0.22 0.719 No
N116Q/M120Y 1c27 A Q130 Y134 0.21 1.616 No
N116H/M120S 1p7g H H87 S91 0.38 1.395 No
N116H/M120N 4hmm B H177 N181 0.25 1.589 No
N116H/M120Y 1xh8 A H142 Y146 0.25 1.632 No
N116K/M120H 2ifq A K39 H43 0.29 1.344 No
N116S/M120H 4toh B S126 H130 0.19 2.279 No
N116S/M120K 4kn8 B S26 K30 0.22 2.416 No
N116S/M120Y 3r3r A S159 Y163 0.5 2.184 No
N116Y/M120T 4cae C Y88 T92 0.29 1.357 No
N116Y/M120Y 3i0z A Y292 Y296 0.49 1.71 No
P143R/K147N 3ix8 A R137 N141 0.49 0.162 No
P143S/K147D 4iqg B S37 D41 0.3 1.171 No
P143T/K147S 3hh1 C T43 S47 0.21 0.114 No
S117N/L121E 4dno B N233 E237 0.39 2.971 No
S117H/L121S 1p7g H H87 S91 0.38 3.571 No
S117W/L121T 1c5v A W237 T241 0.33 2.846 No
S117Y/L121T 4cae C Y88 T92 0.26 3.084 No
A73R/G77R 1qtx B R12 R16 0.3 -0.485 No
A73Q/G77R 2x1c B Q196 R200 0.14 -0.552 No
A73H/G77S 1p7g H H87 S91 0.38 1.981 No
A73H/G77Y 1xh8 A H142 Y146 0.43 0.428 No
A73S/G77H 4toh B S126 H130 0.27 0.28 No
A73S/G77K 4kn8 B S26 K30 0.17 -0.246 No
A73W/G77S 2eij C W146 S150 0.15 1.295 No
W126T/A130S 3hh1 C T43 S47 0.2 2.237 No
E62N/L66T 3bol B N190 T194 0.41 3.205 No
C97T/N101H 3vpc C T148 H152 0.21 2.359 No
R145N/V149T 3bol B N190 T194 0.35 2.803 No
R145H/V149S 1p7g H H87 S91 0.45 2.772 No
R145H/V149N 4hmm B H177 N181 0.28 2.627 No
R145S/V149Y 3r3r A S159 Y163 0.49 2.684 No
A41R/E45H 4xv8 A R48 H52 0.21 0.506 No
A41N/E45T 3bol B N190 T194 0.4 2.717 No
A41D/E45W 4ggo A D205 W209 0.17 0.768 No
A41Q/E45R 2x1c B Q196 R200 0.2 -0.158 No
A41Q/E45Y 1c27 A Q130 Y134 0.16 1.255 No
A41Q/E45H 2gj3 A Q29 H33 0.41 1.304 No
A41H/E45S 1p7g H H87 S91 0.4 1.712 No
A41H/E45Y 1xh8 A H142 Y146 0.3 1.396 No
A41H/E45W 4enq D H251 W255 0.32 0.786 No
A41K/E45N 3lk4 W K237 N241 0.29 1.424 No
A41S/E45H 4toh B S126 H130 0.16 1.615 No
A41S/E45Y 3r3r A S159 Y163 0.44 1.543 No
V75N/L79Y 3vlw B N375 Y379 0.32 2.081 No
V75N/L79T 3bol B N190 T194 0.37 2.091 No
V75Q/L79R 2x1c B Q196 R200 0.34 1.516 No
V75Q/L79Y 1c27 A Q130 Y134 0.31 1.61 No
V75E/L79Y 3ub9 A E48 Y52 0.28 1.588 No
V75H/L79S 1p7g H H87 S91 0.39 2.74 No
V75H/L79N 4hmm B H177 N181 0.36 2.824 No
V75H/L79Y 1xh8 A H142 Y146 0.32 2.547 No
V75K/L79N 3lk4 W K237 N241 0.14 2.411 No
V75K/L79H 2ifq A K39 H43 0.4 2.246 No
V75S/L79H 4toh B S126 H130 0.31 2.631 No
V75S/L79K 4kn8 B S26 K30 0.32 2.383 No
V75W/L79S 2eij C W146 S150 0.32 2.652 No
V75W/L79T 1c5v A W237 T241 0.46 2.385 No
V75W/L79Y 5std C W26 Y30 0.38 1.532 No
V75Y/L79T 4cae C Y88 T92 0.3 2.489 No
A63N/F67E 4dno B N233 E237 0.4 3.265 No
N40R/S44N 3ix8 A R137 N141 0.47 -0.164 No
N40R/S44W 1w35 A R163 W167 0.32 -0.41 No
V149N/F153Y 3vlw B N375 Y379 0.24 2.319 No
V149N/F153T 3bol B N190 T194 0.39 3.249 No
V149D/F153W 4ggo A D205 W209 0.21 2.711 No
V149Q/F153R 2x1c B Q196 R200 0.26 2.641 No
V149H/F153S 1p7g H H87 S91 0.43 3.689 No
V149H/F153N 4hmm B H177 N181 0.3 3.273 No
V149S/F153H 4toh B S126 H130 0.16 3.523 No
V149S/F153K 4kn8 B S26 K30 0.26 3.526 No
V149Y/F153T 4cae C Y88 T92 0.32 3.125 No
K147R/T151R 1qtx B R12 R16 0.31 -1.181 No
K147D/T151W 4ggo A D205 W209 0.19 -0.147 No
K147Q/T151R 2x1c B Q196 R200 0.22 -0.666 No
K147Q/T151Y 1c27 A Q130 Y134 0.32 -0.751 No
K147E/T151Y 3ub9 A E48 Y52 0.23 -0.415 No
K147H/T151S 1p7g H H87 S91 0.34 1.503 No
K147H/T151Y 1xh8 A H142 Y146 0.4 -0.163 No
K147H/T151W 4enq D H251 W255 0.4 -0.24 No
T151N/T155H 3drz B N104 H108 0.45 0.774 No
L39R/K43R 1qtx B R12 R16 0.47 0.335 No
L39R/K43H 4xv8 A R48 H52 0.46 2.182 No
L39R/K43N 3ix8 A R137 N141 0.25 2.354 No
L39R/K43W 1w35 A R163 W167 0.49 1.204 No
L39Q/K43R 2x1c B Q196 R200 0.46 1.191 No
L39Q/K43Y 1c27 A Q130 Y134 0.48 1.54 No
L39E/K43Y 3ub9 A E48 Y52 0.43 1.653 No
L39H/K43N 4hmm B H177 N181 0.44 1.976 No
L39K/K43N 3lk4 W K237 N241 0.49 1.838 No
L39K/K43H 2ifq A K39 H43 0.39 2.599 No
L39S/K43D 4iqg B S37 D41 0.34 2.582 No
L39S/K43H 4toh B S126 H130 0.48 2.29 No
L39T/K43S 3hh1 C T43 S47 0.39 1.878 No
L39T/K43Q 3c9x A T109 Q113 0.41 0.984 No
L39T/K43H 3vpc C T148 H152 0.45 1.647 No
L39T/K43R 3mux A T233 R237 0.23 1.742 No
L39W/K43S 2eij C W146 S150 0.46 1.932 No
L39Y/K43T 4cae C Y88 T92 0.46 2.03 No
L91E/R95Q 2f57 B E646 Q650 0.46 2.56 No
K60R/E64N 3ix8 A R137 N141 0.2 1.013 No
K60E/E64Y 3ub9 A E48 Y52 0.47 0.259 No
K60H/E64N 4hmm B H177 N181 0.48 1.066 No
L66N/D70E 4dno B N233 E237 0.33 2.237 No
E128N/N132T 3bol B N190 T194 0.35 1.672 No
V87E/L121N 4ev8 A E571 N609 0.46 3.851 No
L7N/E11H 3drz B N104 H108 0.46 3.323 No
V71N/V75T 3bol B N190 T194 0.34 2.671 No
V71H/V75S 1p7g H H87 S91 0.41 3.039 No
V71H/V75N 4hmm B H177 N181 0.23 2.799 No
V71K/V75H 2ifq A K39 H43 0.29 2.483 No
V71S/V75H 4toh B S126 H130 0.25 3.542 No
V71S/V75K 4kn8 B S26 K30 0.24 2.947 No
V71T/V75R 3mux A T233 R237 0.5 2.188 No
V71W/V75T 1c5v A W237 T241 0.36 3.164 No
V71W/V75Y 5std C W26 Y30 0.25 2.613 No
V71Y/V75T 4cae C Y88 T92 0.27 2.646 No
I3H/L7N 4hmm B H177 N181 0.47 3.124 No
I3S/L7D 4iqg B S37 D41 0.45 3.823 No
I3S/L7K 4kn8 B S26 K30 0.49 3.368 No
I3T/L7S 3hh1 C T43 S47 0.42 3.648 No
I3T/L7Q 3c9x A T109 Q113 0.42 2.774 No
F67N/V71T 3bol B N190 T194 0.31 3.092 No
F67N/V71E 4dno B N233 E237 0.47 3.085 No
F67D/V71N 4nac B D65 N69 0.46 3.589 No
F67Q/V71Y 1c27 A Q130 Y134 0.27 2.195 No
F67E/V71Y 3ub9 A E48 Y52 0.2 2.34 No
F67H/V71S 1p7g H H87 S91 0.43 3.46 No
F67H/V71N 4hmm B H177 N181 0.2 2.69 No
F67K/V71N 3lk4 W K237 N241 0.34 2.907 No
F67K/V71H 2ifq A K39 H43 0.26 3.092 No
F67S/V71D 4iqg B S37 D41 0.47 3.748 No
S44Q/K48Y 1c27 A Q130 Y134 0.21 -0.201 No
S44H/K48W 4enq D H251 W255 0.28 0.685 No
S44K/K48N 3lk4 W K237 N241 0.25 -0.432 No
P86Q/S90H 2gj3 A Q29 H33 0.39 -0.291 No
R95T/L99H 3vpc C T148 H152 0.31 3.804 No
F114R/L118S 3sxy B R166 S170 0.43 2.754 No
F114S/L118H 4o4t A S19 H23 0.45 2.788 No
K19T/G23D 5df7 B T168 D172 0.42 0.307 No
D70K/G77R 4r0y A K827 R834 0.32 -0.768 No
D70K/G77K 3ly3 A K277 K284 0.45 -0.433 No
N68K/V75K 3ly3 A K277 K284 0.42 0.041 No
A42N/L46T 3bol B N190 T194 0.39 3.781 No
L118N/L133R 3g8d B N90 R111 0.33 3.321 No
D72K/L79K 3ly3 A K277 K284 0.47 -0.115 No
L121D/L133E 2pqr B D101 E121 0.46 3.724 No
L121Q/L133E 3bve B Q88 E142 0.48 3.733 No
L121S/L133Y 2h88 A S497 Y537 0.31 4.102 No
T115R/R119N 3ix8 A R137 N141 0.45 0.035 No
T115K/R119H 2ifq A K39 H43 0.4 -0.01 No
T115S/R119D 4iqg B S37 D41 0.27 0.4 No
D61R/K65R 1qtx B R12 R16 0.25 -0.518 No
D61N/K65T 3bol B N190 T194 0.42 0.406 No
A98S/M102H 4toh B S126 H130 0.19 3.713 No
K19Q/Y25W 1g6i A Q311 W318 0.41 1.007 No
E108S/A112D 4iqg B S37 D41 0.38 2.143 No
E108T/A112S 3hh1 C T43 S47 0.38 1.622 No
T109D/G113W 4ggo A D205 W209 0.47 -0.074 No
T109E/G113Y 3ub9 A E48 Y52 0.47 -0.293 No
T109H/G113S 1p7g H H87 S91 0.44 0.45 No
T109K/G113N 3lk4 W K237 N241 0.47 -0.923 No
T109W/G113W 4tf4 A W287 W291 0.48 0.083 No
A74S/I78H 4toh B S126 H130 0.29 3.805 No
A74T/I78R 3mux A T233 R237 0.48 3.026 No
M6N/D10T 3bol B N190 T194 0.32 2.93 No
E5N/I9Y 3vlw B N375 Y379 0.22 1.776 No
E5H/I9Y 1xh8 A H142 Y146 0.26 1.697 No
E5S/I9H 4toh B S126 H130 0.29 2.283 No
E5S/I9K 4kn8 B S26 K30 0.3 0.321 No
E5T/I9H 3vpc C T148 H152 0.26 1.465 No
V71K/I78R 4r0y A K827 R834 0.5 2.64 No
I150N/R154T 3bol B N190 T194 0.26 3.019 No
M102E/V149T 2y81 A E129 T232 0.49 2.975 No
E45N/A49E 4dno B N233 E237 0.48 1.595 No
E45D/A49N 4nac B D65 N69 0.46 2.3 No
E45Q/A49H 2gj3 A Q29 H33 0.41 0.826 No
E45H/A49S 1p7g H H87 S91 0.39 1.444 No
M120E/N132R 2jjb C E345 R371 0.29 1.801 No
M120T/N132Q 2f7n A T72 Q112 0.29 2.308 No
R96N/I100T 3bol B N190 T194 0.46 3.285 No
R96S/I100H 4toh B S126 H130 0.18 3.288 No
R96T/I100H 3vpc C T148 H152 0.2 3.09 No
Q69N/A73T 3bol B N190 T194 0.37 2.157 No
Q69H/A73Y 1xh8 A H142 Y146 0.37 1.735 No
Q69H/A73W 4enq D H251 W255 0.39 1.69 No
K43N/D47T 3bol B N190 T194 0.39 1.12 No
K43Q/D47R 2x1c B Q196 R200 0.22 -0.418 No
K43Q/D47Y 1c27 A Q130 Y134 0.2 -0.415 No
K43H/D47N 4hmm B H177 N181 0.25 1.708 No
K85R/D89N 3ix8 A R137 N141 0.46 -0.312 No
K85N/D89Y 3vlw B N375 Y379 0.3 0.711 No
K85N/D89T 3bol B N190 T194 0.35 0.428 No
K85N/D89E 4dno B N233 E237 0.45 -0.026 No
K85D/D89N 4nac B D65 N69 0.44 1.53 No
K85D/D89W 4ggo A D205 W209 0.27 0.876 No
K85Q/D89R 2x1c B Q196 R200 0.23 -0.452 No
K85H/D89S 1p7g H H87 S91 0.37 1.066 No
K85H/D89N 4hmm B H177 N181 0.29 0.647 No
K85H/D89W 4enq D H251 W255 0.43 1.011 No
L99N/V103T 3bol B N190 T194 0.4 3.735 No
L99N/V103E 4dno B N233 E237 0.41 3.837 No
L99E/V103Y 3ub9 A E48 Y52 0.16 3.449 No
L99H/V103S 1p7g H H87 S91 0.43 4.024 No
L99H/V103N 4hmm B H177 N181 0.27 3.735 No
L99K/V103N 3lk4 W K237 N241 0.29 3.504 No
L99K/V103H 2ifq A K39 H43 0.31 3.495 No
L99S/V103H 4toh B S126 H130 0.16 4.043 No
L99S/V103K 4kn8 B S26 K30 0.22 4.022 No
L99S/V103Y 3r3r A S159 Y163 0.4 4.109 No
D20S/Y24Q 3lum C S181 Q185 0.35 1.955 No
M102N/M106H 3drz B N104 H108 0.45 3.346 No
M102E/M106E 3we5 B E15 E19 0.21 2.311 No
M102K/M106E 3g9k D K212 E216 0.26 2.347 No
F4N/R8T 3bol B N190 T194 0.43 1.634 No
K65N/Q69Y 3vlw B N375 Y379 0.24 0.875 No
K65N/Q69T 3bol B N190 T194 0.34 1.21 No
K65D/Q69W 4ggo A D205 W209 0.23 0.544 No
K65Q/Q69Y 1c27 A Q130 Y134 0.22 0.233 No
K65E/Q69Y 3ub9 A E48 Y52 0.15 0.5 No
K65H/Q69S 1p7g H H87 S91 0.44 1.199 No
K65H/Q69N 4hmm B H177 N181 0.22 1.175 No
K65H/Q69Y 1xh8 A H142 Y146 0.17 1.061 No
K65H/Q69K 1k3t C H349 K353 0.5 1.178 No
K65H/Q69W 4enq D H251 W255 0.21 0.982 No
D70Q/A74H 2gj3 A Q29 H33 0.45 0.986 No
D70K/A74N 3lk4 W K237 N241 0.37 2.02 No
D70S/A74D 4iqg B S37 D41 0.47 3.019 No
D72R/R76N 3ix8 A R137 N141 0.5 0.314 No
D72R/R76W 1w35 A R163 W167 0.32 0.91 No
D72N/R76T 3bol B N190 T194 0.33 0.647 No
D72N/R76E 4dno B N233 E237 0.46 -0.69 No

Wild protein